Quality control and purity: HPLC, MS and CoA
Verifying identity and purity
High-performance liquid chromatography (HPLC) separates a sample's components and lets you estimate purity, usually expressed as a percentage.
Mass spectrometry (MS) confirms identity by measuring the molecular mass, compared with the sequence's theoretical value.
The certificate of analysis (CoA)
A CoA gathers a batch's analytical results: identity, HPLC purity, MS data, appearance, and often the lot number and date.
It is the reference document that accompanies a research compound and ensures its traceability.
Storage and handling
Peptides are often lyophilised and kept cold; the cold chain and careful handling preserve the compound's integrity.
These good practices are part of a laboratory's quality process, within a strictly research context.
Strictly educational and scientific content. No effect, benefit or human use is described. Products are intended solely for laboratory research (RUO): they are neither medicines nor food supplements. For any health question, consult a qualified professional.